It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Plaquenil flu shot Does plaquenil help sjogren& 39 For pregnant patients, it is recommended to continue use for those patients with SLE, as it leads to less flare-ups and has not been shown to be teratogenic in some trials. However, it is a pregnancy category class C drug, and patients should discuss all medications with their doctor during pregnancy. Back to Index Anti-malarial drugs hydroxychloroquine, chloroquine are considered pregnancy category C drugs. While there is evidence of risk for damage to the eye and ear, if the benefits of these drugs in controlling RA symptoms are judged to outweigh the risks, they may continue to be used during pregnancy. 1,2 Contraindications. Known hypersensitivity to, or retinal or visual field changes associated with quinoline compounds; psoriasis, porphyria, long-term therapy in children; pregnancy category C. Safe use in juvenile arthritis or lactation is not established. For prolonged treatment of lupus or arthritis, adverse effects include the acute symptoms, plus altered eye pigmentation, acne, anaemia, bleaching of hair, blisters in mouth and eyes, blood disorders, convulsions, vision difficulties, diminished reflexes, emotional changes, excessive coloring of the skin, hearing loss, hives, itching, liver problems or liver failure, loss of hair, muscle paralysis, weakness or atrophy, nightmares, psoriasis, reading difficulties, tinnitus, skin inflammation and scaling, skin rash, vertigo, weight loss, and occasionally urinary incontinence. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. For short-term treatment of acute malaria, adverse effects can include abdominal cramps, diarrhea, heart problems, reduced appetite, headache, nausea and vomiting. Plaquenil pregnancy category c Medication And Pregnancy -, Drug Safety in Pregnant & Nursing Women. Plaquenil and sulfasalazine combination Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Plaquenil Oral Uses, Side Effects, Interactions.. HYDROXYCHLOROQUINE SULFATE. Plaquenil hydroxychloroquine sulfate dosing, indications.. Hydroxychloroquine Pregnancy Warnings Animal studies have revealed evidence of fetal harm. Use of chloroquine and other 4-aminoquinolines in high doses and for prolonged durations has been associated with neurological disturbances and interference with hearing, balance, and vision in the fetus. PLAQUENIL is indicated for the suppressive treatment and treatment of acute attacks of malaria due to Plasmodium vivax, P. malariae, P. ovale, and susceptible strains of P. falciparum. It is also indicated for the treatment of discoid and systemic lupus erythematosus, and rheumatoid arthritis. Plaquenil hydroxychloroquine has been shown to improve physical function in up to 80% of patients with rheumatoid arthritis. Plaquenil hydroxychloroquine is commonly used for lupus in children because of less side effects compared to other medications. Plaquenil hydroxychloroquine helps minimize joint damage.