Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take leflunomide with all of your drugs and health problems. Hydroxychloroquine sulfate crush When rheunatoid factor elevates while on plaquenil Hydroxychloroquine and breastfeeding Does hydroxychloroquine cause bone grafts to fail Learn about drug interactions between hydroxychloroquine oral and leflunomide oral and use the RxList drug interaction checker to check drug combinations. Hence, there is a huge unmet need in finding an effective treatment, let alone to have the ability to predict who responds to what treatment. Based on the unique immunosuppressive properties of leflunomide LEF and hydroxychloroquine HCQ, we recently conducted a randomized, double–blind, placebo-controlled proof of concept study. CHICAGO – Combination therapy with leflunomide and hydroxychloroquine met all goals for efficacy, safety, and tolerability among patients with primary Sjögren’s syndrome in a randomized, placebo-controlled pilot study, lending support to evidence suggesting the two drugs have additive benefits. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Do not start, stop, or change the dose of any drug without checking with your doctor. Leflunomide and hydroxychloroquine Leflunomide, Plaquenil, Gabapentin for a 53-year old woman., THU0238 CLINICAL EFFICACY OF LEFLUNOMIDE/HYDROXYCHLOROQUINE COMBINATION. Plaquenil antibioticAralen patient teachingHydroxychloroquine hand osteoarthritis We compare the side effects and drug effectiveness of Hydroxychloroquine sulfate and Leflunomide. The study is created by eHealthMe based on reports of 132,232 people who take Hydroxychloroquine sulfate and Leflunomide, and is updated regularly. On eHealthMe, you can evaluate side effects and drug interactions from 16 million FDA reports. Hydroxychloroquine sulfate vs. Leflunomide side effect.. Leflunomide-hydroxychloroquine combo shows promise in primary Sjögren’s.. Leflunomide-hydroxychloroquine combo shows promise in primary.. Background/Purpose The combination of methotrexate MTX, sulfasalazine SSZ and hydroxychloroquine HCQ triple therapy is a highly effective and well-tolerated treatment in rheumatoid arthritis RA. While MTX is the cornerstone of most successful combination therapies, not all patients are candidates for, or tolerate, MTX. Leflunomide, a disease-modifying anti-rheumatic drug DMARD. Leflunomide is the generic form of the brand-name medicine Arava, which is used to treat rheumatoid arthritis a condition in which the body attacks its own joints. This prescription medication. Hydroxychloroquine Plaquenil, Sanofi Aventis • d-Penicillamine Cuprimine, Merck and Depen Merck. Leflunomide is a disease modifying anti-rheumatic drug utilized for the treatment of RA. The medication is a selective inhibitor of pyrimidine synthesis. Leflunomide has a long half-life.