For batch specific data refer to the Certificate of Analysis. Tocris products are intended for laboratory research use only, unless stated otherwise. Plaquenil and mastocytosis Plaquenil and your eyes Hydroxychloroquine and lupus pregnancy Plaquenil and diiclofenac Chloroquine is an aminoquinoline that is quinoline which is substituted at position 4 by a 5-diethylaminopentan-2-ylamino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis. Chloroquine diphosphate is used as an antimalarial drug and also functions to increase sensitivity of tumor cells to radiation and chemotherapy via inducing autophagy 1. Chloroquine diphosphate has been reported as an adjuvant for radiation and chemotherapy for inducing cell autophagy to anti-cancer cells proliferation or metastasis 2. Chloroquine phosphate is sparingly soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide. For biological experiments, we suggest that organic solvent-free aqueous solutions of Chloroquine phosphate be prepared by directly dissolving the crystalline solid in aqueous buffers. We invite you to request* or download your copy today! Keywords: Chloroquine diphosphate, Chloroquine diphosphate supplier, Chloroquine, diphosphate, antimalarial, antitumor, antimetastatic, autophagy, apoptosis, Other, Apoptosis, Autophagy, Antimalarials, 4109, Tocris Bioscience $50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image $25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image Tocris offers the following scientific literature in this area to showcase our products. Chloroquine solubility in dmso Chloroquine and hydroxychloroquine inhibit bladder cancer., APExBIO - Chloroquine diphosphateAntimalarial drugCAS. Plaquenil treatment for vasculitisDoes hydroxychloroquine cause high blood pressure What volume of solvent to add to compound powder to obtain a mM stock? I have 1.09 mg of compound X with a molecular weight of 434.92. I want to make a 50 mM stock solution in DMSO. What volume of solvent to add to compound powder to obtain.. RODT INRMATIN - Home Cayman Chemical. Chloroquine diphosphate ≥99%HPLC Selleck ATM/ATR.. The solubilities of chloroquine diphosphate and 4,7-dichloroquinoline in water, ethanol, tetrahydrofuran, acetone, and acetonitrile were measured over the temperature range of 298.2 to 333.2 K. The solubilities of both analytes in different solvents increase smoothly with temperature. On the basis of the solubility data, it can be observed that the highest solubilities for chloroquine. In Vitro In vitro activity Chloroquine is a chemotherapeutic agent for the clinical treatment of malaria. Chloroquine is able to bind to DNA, and inhibit DNA replication and RNA synthesis which in turn results in cell death. The effect of Chloroquine may also be related to the formation of a toxic heme-Chloroquine complex. Solubility of Chloroquine Diphosphate and 4,7-Dichloroquinoline in Water, Ethanol, Tetrahydrofuran, Acetonitrile, and Acetone from 298.2 to 333.2 K. Journal of Chemical & Engineering Data 2009, 54 8, 2170-2173. DOI 10.1021/je8007099.