Hydroxychloroquine retinopathy pathogenesis

Discussion in 'Canadian Drug' started by Televizor, 08-Mar-2020.

  1. SoftHunter XenForo Moderator

    Hydroxychloroquine retinopathy pathogenesis


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    Risk factors that increase the chance of hydroxychloroquine retinopathy include daily dosage, cumulative dose, renal or liver disease, age, and previous retinal disease 9. A daily dose of 6.5mg/kg ideal body weight places patients at higher risk, but a daily dose below this level did not preclude the patient from developing toxicity after. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Abstract Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools.

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    Hydroxychloroquine retinopathy pathogenesis

    Hydroxychloroquine An old drug with new relevance., Hydroxychloroquine-Induced Retinal Toxicity - American.

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  6. Revised recommendations on screening for chloroquine and hydroxychloroquine retinopathy. Ophthalmology 2011;15. 17. Browning DJ, Lee C. The relative sensitivity and specificity of 10-2 visual fields, multifocal electroretinography, and spectral domain optical coherence tomography in detecting hydroxychloroquine and chloroquine retinopathy.

    • Avoiding the Traps of Hydroxychloroquine Use.
    • Recommendations on Screening for Chloroquine and..
    • Chloroquine retinopathy - Wikipedia.

    Chloroquine and hydroxychloroquine belong to the quinolone family. Although their therapeutic and toxic doses differ, they are related drugs with similar clinical indications for use and similar manifestations of retinal toxicity. The image below depicts hydroxychloroquine retinopathy. Jul 14, 2017 The pathogenesis of HCQ-induced retinal toxicity is not fully understood. Recommendations on screening for chloroquine and hydroxychloroquine retinopathy 2016 revision. Hydroxychloroquine Plaquenil and chloroquine cause ocular toxicity to various parts of the eye such as the cornea, ciliary body, and retina. Chloroquine can also induce cataract formation; however, no reports of hydroxychloroquine and cataract have been reported. This article focuses upon hydroxychloroquine retinopathy. Disease

     
  7. ShiJaG New Member

    Hydroxychloroquine is widely used in the treatment of post-Lyme arthritis. Hydroxychloroquine MedlinePlus Drug Information Compare Plaquenil vs Chloroquine - Hydroxychloroquine Plaquenil thread COVID19
     
  8. su_re New Member

    Combination hydroxychloroquine and sulfasalazine - HealthUnlocked Hi there. Sulphasalasine was helpful in my case but took 12 weeks to kick in. After a while it wasn't as effective and I too was prescribed methotrexate alongside. The side effects of the methotrexate for me were horrendous chronic chest infections and I'm now asthmatic as a result.

    Methotrexate, Plaquenil or Sulfasalazine Azulfidine. - Inspire