One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Chloroquine plaquenil Chloroquine cell signalling Plaquenil arthritis treatment Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy 2016 Revision. Marmor MF1, Kellner U2, Lai TY3, Melles RB4, Mieler WF5; American Academy of Ophthalmology. Author information 1Department of Ophthalmology and Byers Eye Institute, Stanford University School of Medicine, Palo Alto, California. We report an unusual case of hydroxychloroquine HCQ toxicity after only 2 months of starting the treatment. A 42-year-old woman presented with visual impairment. Her visual acuity was 20/20 in the right eye and 20/25 in the left eye. Ophthalmologic. Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy 2016 Revision. Marmor MF1, Kellner U2, Lai TY3, Melles RB4, Mieler WF5; American Academy of Ophthalmology. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. 2016 ophthalmology journal hydroxychloroquine Table of Contents page Ophthalmology Retina, Macular toxicity after short-term hydroxychloroquine therapy Could you develop a rash 3 weeks after starting hydroxychloroquine In 2016, the American Academy of Ophthalmology published recommendations on screening for chloroquine and hydroxychloroquine retinopathy. The primary screening tests are automated visual fields plus spectral-domain optical coherence tomography SD-OCT. Effect of Hydroxychloroquine on the Retinal Layers A.. Recommendations on Screening for Chloroquine and.. Hydroxychloroquine Blood Levels Predict Hydroxychloroquine Retinopathy.. Purpose. To evaluate the effect of hydroxychloroquine on retinal pigment epithelium- RPE- Bruch’s membrane complex, photoreceptor outer segment, and macular ganglion cell-inner plexiform layer GCIPL thicknesses using spectral-domain optical coherence tomography SD-OCT. Methods. In this prospective case-control study, 51 eyes of 51 hydroxychloroquine patients and 30 eyes of 30 healthy. Marmor MF, Kellner U, Lai TYY, Melles RB, Mieler WF, for the American Academy of Ophthalmology. Recommendations on screening for chloroquine and hydroxychloroquine retinopathy 2016 revision. Ophthalmology 2016;186-1394. Melles RB, Marmor MF. The risk of toxic retinopathy in patients on long-term hydroxychloroquine therapy. This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative.