With this condition, exposure to cold causes blood vessels in the fingers and toes to spasm, leaving the digits feeling frigid and numb—and occasionally blue. Plaquenil, used to decrease joint pain and swelling, is approved by the Food and Drug Administration for the treatment of lupus and rheumatoid arthritis. Hydroxychloroquine in sle Hydroxychloroquine forum Doctors have used hydroxychloroquine as an off-label alternative. Prescription drugs are licensed for certain conditions off-label use means doctors are using them to treat illnesses outside of. Plaquenil Hydroxychloroquine is used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus & others. Findings do not support the current practice of off-label use of hydroxychloroquine in patients with hand osteoarthritis, but that should not deter research and drug development communities from researching more potent agents or compounds that more specifically target the inflammatory pathways, editorialists said. But many doctors (myself included) sometimes prescribe a drug for another indication or different population or age group than those for which it’s FDA-approved. But my patient insisted that she had never been diagnosed with either condition. FDA approval means evidence has shown that a drug is safe and effective for a specific disease or symptom. Hydroxychloroquine off label uses Hydroxychloroquine - Off label use drug - Ovarian cancer., Plaquenil Hydroxychloroquine - Side Effects, Dosage. Plaquenil ear ringingChloroquine and sun exposureWhorl keratopathy plaquenilPlaquenil and low blood sugarPlaquenil bledding Hydroxychloroquine is used for treating rheumatoid arthritis and lupus. It is also approved to prevent and treat certain types of malaria in adults and children. Healthcare providers may occasionally prescribe the drug "off-label" for other conditions as well. What Is Hydroxychloroquine Used For?. Off-label hydroxychloroquine no more effective than.. Off-Label Prescription Drugs Use Benefits and Risks. Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Corticosteroids and salicylates may be used in conjunction with PLAQUENIL, and they can generally be decreased gradually in dosage or eliminated after a maintenance dose of PLAQUENIL has been achieved. HOW SUPPLIED. PLAQUENIL tablets are white, to off-white, film coated tablets imprinted “PLAQUENIL” on one face in black ink. Each tablet.