Common symptoms of optic neuritis include pain with eye movement and temporary vision loss in one eye., optic nerve inflammation can occur with other conditions, including infections or immune diseases, such as lupus. Rarely, another disease called neuromyelitis optica causes inflammation of the optic nerve and spinal cord. Icd 10 data plaquenil Plaquenil ocular side effects Ischemic optic neuropathy - or injury to the optic nerve presumed to be caused by reduced blood flow - is the most frequent, acute optic neuropathy in patients over the age of 50 and the second-most common cause of severe vision loss in adults with glaucoma. Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use. Doctors probably assumed that the nerve issues were due to the lupus in those patients. Plaquenil was never really a popular treatment. It does cause damage to the nerves in the retina for some people too.is probably an effect that was just very noticeable at first and the other nerve damage was less visible. Sometimes steroid medications may speed the recovery of vision after optic neuritis. It's believed to develop when the immune system mistakenly targets the substance covering your optic nerve, resulting in inflammation and damage to the myelin. Most people who have a single episode of optic neuritis eventually recover their vision without treatment. Optic neuropathy due to plaquenil Know Your Systemic Meds The Top 10 to Track, Rx Side Effects New Plaquenil Guidelines and More - American. What is hydroxy chloroquine This compressive optic neuropathy may cause cupping resembling glaucoma, as well as glaucoma-like visual field defects. The difference, again, is the optic nerve appearance, pallor out of proportion to cupping, as well as color vision loss and unilateral visual acuity loss. When Glaucomatous Damage Isn’t Glaucoma. Plaquenil causes and treats neuropathy? - NeuroTalk Support.. Eye problems? Medications may be the culprit - All About Vision. Elevated liver enzymes, nausea, fatigue, cytopenia, stomatitis, bone marrow suppression and liver cirrhosis have been reported as systemic side effects of methotrexate89101112. Ocular side effects include irritation and dry eye 13, as well as the rare occurrence of toxic optic neuropathy. Most people have some permanent optic nerve damage after an episode of optic neuritis, but the damage might not cause permanent symptoms. Decreased visual acuity. Most people regain normal or near-normal vision within several months, but a partial loss of color discrimination might persist. Peripheral neuropathy is found among people who take Plaquenil, especially for people who are female, 60+ old also take medication Methotrexate, and have High blood pressure. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated.