Acute chloroquine poisoning

Discussion in 'Canadian Pharcharmy' started by Hijara, 24-Feb-2020.

  1. Denio Guest

    Acute chloroquine poisoning


    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

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    Acute chloroquine intoxication is responsible for a hypokalaemia which correlates with the gravity of the intoxication and may be due to a transport-dependent mechanism. Plasma potassium concentrations should be carefully observed, particularly among patients who also receive catecholamine infusions. Abstract. Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. In addition, chloroquine is prescribed as therapy for certain connective tissue disorders. Consequently, there are many opportunities for children to be poisoned through chloroquine ingestion. To alert medical practitioners and the public to this danger, the following cases of chloroquine poisoning recently reported to CDC are presented.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Acute chloroquine poisoning

    Chloroquine and Hydroxychloroquine Toxicity Practice., Recommendations on Screening for Chloroquine and.

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  6. In the recent study two cases of the acute chloroquine poisoning, hospitalized in the Toxicology Department in Kraków, were described and one of them was fatal. The first case was 16-year-old girl who ingested 5 g of chloroquine phosphate in the suicidal attempt.

    • Acute chloroquine intoxication--rare, but always serious..
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    EUROPEAN JOURNAL OF PHARMACOLOGY 25 1974 210-215. NORTH-HOLLAND PUBLISHING COMPANY EFFECT OF HYPERTHERMIA ON ACUTE CHLOROQUINE TOXICITY IN RABBITS E. AYITEY-SMITH, G. L. BOYE, N. NICHANI and R. A. LEWIS Department of Pharmacology, University of Ghana Medical School, P. O. B. 4236, Accra, Ghana Received 3 July 1973 Accepted 22 October 1973 E. AYITEY-SMITH, G. L. BOYE, N. NICHANI and R. A. LEWIS. Quinine and chloroquine poisoning are characterized by severe cardiovascular toxicity resulting from sodium and potassium channel blockade, leading to hypotension, shock, arrhythmias and cardiac arrest. Quinine poisoning can cause irreversible visual loss. Severity of symptoms is closely related to the ingested dose and plasma concentration. Single-dose activated charcoal can be given within 1. One hundred sixty-seven consecutive patients with acute chloroquine overdose admitted to our toxicology ICU. The mean amount ingested by history was 4.5 +2- 2.8 g. and 43 26% of 167 patients ingested 5 g. The mean blood chloroquine concentration on admission was 20.5 +/- 13.4 mumol/L.

     
  7. runetseo Guest

    Information about drug Hydroxychloroquine includes cost of the drug and the type of drug - tablet, capsule, syrup, cream, gel, ointment, liquid or injection. Savings Chart Costco Hydroxychloroquine Price Comparison Uses, Dosage, Form. Buy Cheap Plaquenil Online
     
  8. forscripts Moderator

    Quinine was frequently prescribed as an off-label treatment for leg cramps at night, but this has become less common due to a warning from the US Food and Drug Administration (FDA) that this practice is associated with life-threatening side effects. Antimalarial Agents Chloroquine, Hydroxychloroquine, and. Chloroquine Indications, Side Effects, Warnings - Comparative study of chloroquine and quinine on malaria.
     
  9. BATCOH Moderator

    Hydroxychloroquine - Wikipedia Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth.

    Medicines for the Prevention of Malaria While Traveling.
     
  10. KAP User

    Hydroxychloroquine - thigh muscle weakness? Jun 25, 2013 Hi, although Plaquenil is prescribed for autoimmune diseases, such as yours, it can actually add to/increase the number of the symptoms. Muscle damage and leg pain being just 2 examples. It is great that you have responded so well to the new medication.

    Do You Have Nerve Pain in Your Thigh? Here's What You Need to.