Norwich, New York of the Excellence in Geriatric Pharmacy Practice Award from the Commission for Certification in Geriatric Pharmacy. Applies to hydroxychloroquine: oral tablet Along with its needed effects, hydroxychloroquine (the active ingredient contained in Plaquenil) may cause some unwanted effects. Chloroquine structure Chloroquine physical properties The condition remains underdiagnosed because of underreporting of signs and symptoms. Another reason for lack of treatment is the belief that antidepressants have proconvulsant effects. Many antidepressants are known to lower the seizure threshold; however, data indicate that, at low doses. Aug 14, 2017 Tramadol, a powerful narcotic pain reliever, can lower the seizure threshold, reports the medical reference website The likelihood of seizures associated with tramadol use increases in patients concurrently taking antidepressants, antipsychotic medications and other narcotics. Drugs that May Lower Seizure Threshold ; Drug Treatment. Seizure meds and plaquenil. The mission of the Epilepsy Foundation is to lead the fight to overcome. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Although not all of these side effects may occur, if they do occur they may need medical attention. Plaquenil lower seizure threshold Common Causes of Drug-Induced Seizures - U. S. Pharmacist, Drugs That Lower the Seizure Threshold Healthfully Chloroquine phosphate tablet ip 250 mgPlaquenil killsHydroxychloroquine toxicity octWhat class of drugs is hydroxychloroquineChoi et al 2014 chloroquine paclitaxel Because I have epilepsy I have a lowered seizure threshold, so various drugs can be more problematic - then again, I am often able to take them without a problem, particularly at lower doses etc etc. The classic drug for interacting is coumadin, as those of us who are on it know only two well. It interacts with practically everything. Plaquenil & other drug interactions ? Lupus Forums at.. Seizure meds and plaquenil Epilepsy Foundation. What is a Seizure Threshold? with pictures. Feb 24, 2008 Because I have epilepsy I have a lowered seizure threshold, so various drugs can be more problematic - then again, I am often able to take them without a problem, particularly at lower doses etc etc. The classic drug for interacting is coumadin, as those of us who are on it know only two well. It interacts with practically everything. Jan 01, 2020 Mefloquine and other drugs known to lower the convulsive threshold Plaquenil can lower the convulsive threshold. Co-administration of Plaquenil with other antimalarials known to lower the convulsion threshold e.g. mefloquine may increase the risk of convulsions. Seizure activity during the ECT procedure is affected by medication as well. Administration of seizure threshold increasing drugs should be reviewed and where possible stopped or reduced. If the treatment is for depression, consider using tricyclic drugs which lower the seizure threshold and augment ECT.