Corticosteroid therapy should be instituted if the patient has clinically significant renal disease. Use immunosuppressive agents, particularly cyclophosphamide, azathioprine, or mycophenolate mofetil, if the patient has aggressive proliferative renal lesions, as they improve the renal outcome. Hydroxychloroquine instructions When taking plaquenil which tests should periodically be taken Plaquenil toxicity diagnosis code Chloroquine generic name Lupus Nephritis Inflammation of the nephrons, the structures within the kidneys that filter the blood, is called glomerulonephritis, or nephritis. Lupus nephritis is the term used when lupus causes inflammation in your kidneys, making them unable to properly remove waste from your blood or control the amount of fluids in your body. Learn about the wide-ranging effects of hydroxychloroquine Plaquenil® in the treatment of lupus dosing, benefits, side effects and rare complications of this commonly prescribed medication. Lupus nephritis is a severe and potentially life-threatening type of kidney disease caused by lupus. Up to 60 percent of people with lupus will develop lupus nephritis and 10 percent will develop end-stage renal disease due to lupus nephritis. Calcineurin inhibitors, especially tacrolimus, have demonstrated benefit in lupus nephritis. Immunosuppressives can also be used if the patient has an inadequate response or excessive sensitivity to corticosteroids. Lupus nephritis and plaquenil Lupus Nephritis Medication Corticosteroids., Drug spotlight on hydroxychloroquine Lupus Foundation of. Hydroxychloroquine other namesPlaquenil discontinued Proliferative Lupus Nephritis Treatment With Chloroquine and Hydroxychloroquine The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U. S. Federal Government. Proliferative Lupus Nephritis Treatment With Chloroquine.. What is Lupus Nephritis?. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Hydroxychloroquine is one of the medications recommended for the management of lupus and lupus nephritis in pregnant women. If pregnancy is detected during therapy, it should not be stopped could precipitate a flare in maternal disease and exposure to the fetus will still continue for 6 to 8 weeks due to tissue binding Baer 2011; Bertsias 2012; Hahn 2012; Levy 2001. Summary Lupus nephritis is found among people who take Plaquenil, especially for people who are female, 20-29 old, have been taking the drug for 6 - 12 months, also take medication Cellcept, and have Pain. Systemic lupus erythematosus SLE is a chronic, multisystem, inflammatory disorder of autoimmune etiology, occurring predominantly in young women. Common manifestations may include arthralgias and arthritis, Raynaud phenomenon, malar and other rashes, pleuritis or pericarditis, renal or CNS involvement.