The condition often accompanies other immune system disorders, such as rheumatoid arthritis and lupus. In Sjogren's syndrome, the mucous membranes and moisture-secreting glands of your eyes and mouth are usually affected first — resulting in decreased tears and saliva. Your immune system mistakenly attacks your body's own cells and tissues. How to take chloroquine phosphate 500 mg Drug treatment of chloroquine resistant malaria Does plaquenil change heart rate I've kinda noticed the same thing but I have a lactose intolerance. It wasn't as severe as it was when I was a child until I started Plaquenil. When I started Plaquenil almost 2 months ago I assumed the GI issues were a side effect and it would eventually go away but it hasn't. I'm going to bring it up to my rheumy when I see him. Lymphoma represents a relatively well-recognized malignant phenomenon associated with lupus. The cause and effect relationships of lymphoma in SLE have been subject to extensive scrutiny with several studies reporting on clinic-pathologic characteristics and risk factors predicting lymphoma development in SLE. Lymphocytic colitis is a rare disorder causing inflammation in the intestine. It is a form of IBS caused by immune cells building up and attacking the tissues in the intestine, resulting in inflammation and swelling. Certain genes put people at higher risk of the disorder, but it appears that a triggering mechanism — such as infection with a particular virus or strain of bacteria — is also necessary. Scientists aren't certain why some people develop Sjogren's syndrome. Plaquenil lymphoma Rheumatoid Arthritis and Lymphoma What's the Link?, SLE and Non-Hodgkin’s Lymphoma A Case Series and Review. Colchine as a trail vs plaquenil May 16, 2017 Dr Bernatsky As is seen in the general population, lymphoma risk in SLE appears to be higher in men than women, and risk increases with age. A study conducted by our team examined demographic factors of patients with SLE who developed non-Hodgkin lymphoma. Lymphoma in Patients With Systemic Lupus Erythematosus.. Lymphocytic Colitis Causes, Symptoms, Treatment, and Diet. Study Raises Questions about Sjogren's and Plaquenil. Although this connection may concern you, it’s important to bear in mind that lymphomas are relatively rare. One of the most common forms, non-Hodgkin lymphoma, occurs in about one in 50 adults in the United States 2% – which means that your risk as a person with RA grows to about two in 50 4%. Data from case series and retrospective and open-label studies support the use of hydroxychloroquine in the treatment of extensive cutaneous sarcoidosis Chong 2005, Jones 1990, Modi 2008. Contraindications. Known hypersensitivity to hydroxychloroquine, 4-aminoquinoline derivatives, or any component of the formulation. Hydroxychloroquine Plaquenil is another option and is generally considered safer than methotrexate. However, these prescribed drugs have a range of side effects such as nausea, loss of appetite, dizziness, hair loss, stomach aches/cramps, headache, liver toxicity, and increased risk of infections.