Cutaneous hyperpigmentation during therapy with hydroxychloroquine

Discussion in 'Hydroxychloroquine 200 Mg Tab' started by sfd, 29-Feb-2020.

  1. Cutaneous hyperpigmentation during therapy with hydroxychloroquine


    B, Brown pigmentation on the legs in another patient who had systemic lupus erythematosus associated with diffuse discoid lupus. The skin biopsy was performed on the brown area distant from discoid lesions.

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    An elderly woman presented with 6 months history of skin coloured to erythematous papules in annular pattern over extremities, upper back and neck. The patient was diagnosed with granuloma annulare GA and started on hydroxychloroquine HCQ 300 mg daily. After 4 months of treatment, she developed bluish grey pigmentation within the plaques of GA with normal surrounding skin figure 1A,B. Reactions 1565, p109 - Cutaneous hyperpigmentation 4 case reports Four men developed cutaneous hyperpigmentation during treatment with doxycycline and hydroxychloroquine routes not stated. A 75-year-old man with chronic Q fever received doxycycline 200 mg/day; he had been receiving hydroxychloroquine 400 mg/day for 5 years for rheumatoid arthritis. After 4 months, his. Some side effects of hydroxychloroquine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

    B, Presence of iron in the same areas of the dermis (Perls staining, original magnification ×100). Pub Med Google Scholar Crossref Morrison LK, Nordlund JJ, Heffernan MP. Pub Med Google Scholar Costedoat-Chalumeau N, Galicier L, Aumaître O, et al; Group PLUS. Google Scholar Costedoat-Chalumeau N, Amoura Z, Hulot JS, et al. Pub Med Google Scholar Crossref Costedoat-Chalumeau N, Leroux G, Piette J-C, Amoura Z. A, Interstitial and perivascular brown pigmented granules in the dermis (hematoxylin-eosin-safran staining, original magnification ×100).

    Cutaneous hyperpigmentation during therapy with hydroxychloroquine

    Cutaneous Hyperpigmentation During Therapy With Hydroxychlor., Doxycycline/hydroxychloroquine, Reactions Weekly 10.1007.

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  5. Hydroxychloroquine does cross the placenta and is considered Category D in pregnancy see DermNet NZ's pages on Safety of medicines taken during pregnancy and on Lactation and the skin. However, in multiple studies, hydroxychloroquine use has not been associated with congenital disabilities, stillbirth, prematurity, low birth weight, fetal.

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    Hydroxychloroquine HCQ-associated hyperpigmentation is uncommon, with onset ranging from 3 months to 22 years following the initiation of therapy 1. A 32-year-old woman presented with a 1.5-year history of symmetric polyarthritis, positive rheumatoid factor, and anticyclic citrullinated peptide antibody, without erosive joint changes. Background Antimalarials including hydroxychloroquine HCQ have been used in the treatment of systemic lupus erythematosus SLE for more than 50 years. Few cases of hyperpigmentation attributed to HCQ have been reported in the literature from different geographical areas. BACKGROUND Hydroxychloroquine sulfate and other antimalarial drugs have been used successfully as adjunctive therapy for patients with cutaneous lesions of dermatomyositis over the past 20 years. An increased incidence of cutaneous reactions to hydroxychloroquine has been postulated to occur in patients with dermatomyositis.

     
  6. coding Moderator

    Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. Plaquenil, Plaquenil Sulfate, Quineprox hydroxychloroquine. Hydroxychloroquine Professional Patient Advice -
     
  7. Eat_my_shorts Moderator

    Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Despite Plaquenil dosing recommendations, retinal toxicity. Hydroxychloroquine retinopathy — implications of research. Chloroquine - Wikipedia
     
  8. alexii User

    Safety of Chloroquine in Pregnancy JAMA JAMA Network The editorial alludes to chloroquine as "yet another drug which is apparently toxic to the developing fetus." In the 20-year period that chloroquine has been available, it has been used by an estimated 1 billion people—by the armed forces of the United States, the armed forces of other nations, and the populations in malarious areas.

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