This includes questioning the safety of topical products -- such as sunscreens -- over fear that they may cause birth defects. Haglund's syndrome is an inflammatory condition that could affect the area around your heel, where a small fluid-filled sac, called a bursa, allows the Achilles' tendon to slide smoothly over the bony ridge of your calcaneus (heel bone). Pain when stopping hydroxychloroquine plaquenil Plaquenil and mixed connective tissue disease Adverse effects of plaquenil menstrual cycle Hydroxychloroquine plaquenil direct sun light While side effects of corticosteroids are usually to blame, there is also the possibility of ocular damage associated with long-term use of the antimalarial drugs hydroxychloroquine brand name Plaquenil® and chloroquine. Improved vision screening tests and updated dosing guidelines are key to avoiding such complications. I just joined this forum but I have been treated for SLE Lupus since 2001. I have been on Plaquenil ever since. My last retina scan shows some thinning of the retina so I am being scheduled with a specialist for further testing and I have been told there is a good possibility I will have to stop taking Plaquenil. Hydroxychloroquine has significantly less retinal toxicity and has largely replaced chloroquine as a treatment of inflammatory disease. Unfortunately, the retinal damage from these medications is largely irreversible, so it is critical to detect early retinal toxicity in the hopes of limiting the extent of visual loss. Sign/Symptoms Additionally, another exception occurred while executing the custom error page for the first exception. Description: An exception occurred while processing your request. Retinal damage from plaquenil Conditions Plaquenil-related Eye Problems Eugene Eye Care, Has anyone had retinal damage from Plaquenil? - Lupus. Drugs.com hydroxychloroquinePlaquenil works for what diseasesDoses of hydroxychloroquineChemical process of chloroquineEosinophilotaxis hydroxychloroquine Retinal Damage. According to Drugs.com, Plaquenil given for a long term can cause retinal disorders after a few months or years of daily use--especially if the dose exceeds 400mg per day. The risk of retinal damage increases at doses of 600mg to 700mg. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis. Hydroxychloroquine Plaquenil Toxicity and Recommendations.. Plaquenil Side Effects Common, Severe, Long Term -. Your ophthalmologist can use this image to look for early retinal damage. Multifocal ERG This test looks at cells in the retina called rods and cones. The test measures how well these cells respond to light. It can find retinal damage from Plaquenil. Photos A special camera takes pictures of the retina. Photos show damaged areas as small. Ocular findings of HCQ retinal toxicity as detected by various screening modalities. A female patient was diagnosed with HCQ retinal toxicity at the age of 53 years, having taken HCQ for 12 years at 400 mg/day. She was not obese and had no additional risk factors for toxicity. The mechanism by which antimalarial medications cause retinal toxicity involves the binding of the drugs to the melanin in the pigmented epithelial layer of the retina, and subsequent damage to rods and cones. Retinal toxicity had been classically characterized as involving bilateral “bull’s-eye” maculopathy, initial photoreceptor damage.