Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Arava and plaquenil What are similar drugs to plaquenil Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Anti-malarial medications have shown to improve muscle and joint pain, skin rashes, pericarditis, and other lupus symptoms such as fatigue and fever. such as the kidney and central nervous system your brain and spinal cord and may help to reduce flares by as much as 50%. Plaquenil and other anti-malarials are the key to controlling lupus. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Does plaquenil reduce pain Plaquenil and its affect on the immune system DailyStrength, Treating Lupus with Anti-Malarial Drugs Johns Hopkins. Gastritis plaquenilHydroxychloroquine lupus side effectsHydroxychloroquine elimination Hi - I just started Plaquenil 400 mg a day two week ago and I started feeling less achy and tired a few days ago. Is it possible for it to work quicker in some people? I've heard it can take months, but I must say that I haven't felt like this since I was a kid - not achy or stiff. Has anyone had a similar Immune & Autoimmune - Lupus Plaquenil - Can It Work Quickly?. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. RA and Hydroxychloroquine How Effective is it for.. Yes, plaquenil is difficult to adjust first, but after the first year of treatment and side effects, the benefits outweigh the problems. So, stick with it. In my opinion, the plaque nil is keeping the immune system regulated and the pain and other symptoms described will reduce. Lupus is not an illness without pain or sacrifice, but, it’s. Plaquenil What You Need to Know. Contents What is Plaquenil. Reduce muscle and joint pain; Reduce lupus related rashes; Protect against pleuritis inflammation of the lining of the lungs. of generic hydroxychloroquine can sometimes cause stomach irritation that usually does not occur with the brand name Plaquenil. Your doctor can make. I have been on Plaquenil for years. It has not helped me with fatigue. Things like vitamins and exercise might assist with decreasing the fatigue level. I have been on 2 Dmards and a biologic for the longest time. I also take Tramadol for pain and now Indomethicin has been added to the mix to help with stiffness.