Derm Net NZ Medical Editor: Dr Delwyn Dyall-Smith, Dermatologist, Wagga Wagga, NSW, Australia. However, following an identical dose of hydroxychloroquine and chloroquine, tissue levels of chloroquine are 2.5 times those of hydroxychloroquine. Derm Net NZ Editor in Chief: Adjunct Prof Amanda Oakley, Dermatologist, Hamilton, New Zealand. Hydroxychloroquine is preferred due to its safer profile. Chloroquine resistance Chloroquine and sun exposure Chloroquine vs hydroxychloroquine autophagy Is plaquenil making my skin age and wrinkle fast Objective To critically appraise the body of literature concerning treatment of lichen planus LP. Design Review of MEDLINE and BIOSIS databases to identify articles published with at least an English abstract before March 1998 that examined treatment of Outcome Measures. Lichen planopilaris. Primary treatment is focused on anti-inflammatory modulation. More common medications used are monthly intralesional triamcinolone acetonide at 3-10 mg/mL, prednisone, and systemic retinoids, although hydroxychloroquine and other immune suppressants particularly mycophenolate mofetil are also used. Primary cicatricial alopecias PCAs, rare disorders that lead to permanent hair loss, have been poorly understood and are difficult to treat. Lichen planopilaris LPP is a prototypical PCA; patients often present with sudden onset of hair loss and clinically significant symptoms of itching, burning, and pain of the scalp. Hydroxychloroquine is considered safer than chloroquine during pregnancy and lactation. If there is a of hydroxychloroquine, although studies have not usually confirmed this clinical impression. Hydroxychloroquine dose for lichen planopialris Treatment Options for Lichen Planopilaris What to., Scarring Alopecia Treatment & Management Medical Care. Plaquenil for vasculities rashPlaquenil maculopathy photos Background Lichen planopilaris is an inflammatory cicatricial alopecia, and its management is a challenge for dermatologists. We aimed to compare the efficacy of methotrexate and hydroxychloroquine on refractory lichen planopilaris. Methods In a randomized clinical trial, 29 patients were randomly allocated to receive either 15 mg methotrexate/week or 200 mg hydroxychloroquine twice a day. Clinical efficacy and safety of methotrexate versus.. Lichen Planopilaris Treated With a Peroxisome Proliferator.. Hydroxychloroquine vs. Clobetasol Rinse to Treat Oral.. A case report for a patient with lichen planopilaris LPP revealed significant hair regrowth when originator adalimumab Humira was added to the patient’s hydroxychloroquine regimen. Adalimumab was originally prescribed for rheumatoid arthritis RA and hidradenitis suppurativa HS. Lichen planus on the skin often clears up on its own in months to years. If the disease affects your mucous membranes, it tends to be more resistant to treatment and prone to recur. Other oral medicines used in selected situations for this condition are the antimalarial hydroxychloroquine Plaquenil and the antibiotic metronidazole Flagyl. You should take hydroxychloroquine with or immediately after food. What dose should I take? Your doctor will advise you about this. Usually you will be started on a full dose for example, 400 mg daily or 2 tablets of 200mg hydroxychloroquine and later your doctor may reduce the dose for example, to 200 mg daily of hydroxychloroquine.