I've stopped Sulfa as I was experiencing a bad taste & smell, which may be caused by sulfa. After a while it wasn't as effective and I too was prescribed methotrexate alongside. I'm about to start MTX & am hoping that I wont have side effects with that! The side effects of the methotrexate for me were horrendous (chronic chest infections) and I'm now asthmatic as a result. 30-2 plaquenil Can i take plaquenil if i have macular degeneration Malaria resistant to chloroquine Chloroquine walgreens SULFASALAZINE is for ulcerative colitis and certain types of rheumatoid arthritis. The lowest GoodRx price for the most common version of sulfasalazine DR is around $21.28, 59% off the average retail price of $52.37. Compare Methotrexate vs Sulfasalazine head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Methotrexate rated 6.7/10 vs Sulfasalazine rated 5.7/10 in overall patient satisfaction. Background/Purpose The combination of methotrexate MTX, sulfasalazine SSZ and hydroxychloroquine HCQ triple therapy is a highly effective and well-tolerated treatment in rheumatoid arthritis RA. While MTX is the cornerstone of most successful combination therapies, not all patients are candidates for, or tolerate, MTX. I had side effects from MTX, which largely wore off, but haven't had any problems with the Hydroxy or Sulpha. I refuse to take it now even if its my passport to biologic treatment. I started with MTX which worked, but not enough so the others were added in which has been better. Sulfasalazine vs plaquenil Sulfasalazine Oral Uses, Side Effects, Interactions, Pictures., Methotrexate vs Sulfasalazine Comparison - Hydroxychloroquine breast cancerPlaquenil keep you awake I took it when first diagnosed and turned out to have a terrible allergy-not to the sulfa, but to the quinine in the drug. The itching was unreal and took 3 weeks to get our of my system. I do take sulfasalazine-another sulfa drug that doesn't act like one. My rhuemy told me not to take any others because some regular slafa drugs can cause flares. Plaquenil and Sulfa Allergies" Lupus Community - Support Group. Leflunomide, Sulfasalazine and Hydroxychloroquine for.. The official site for Sulfasalazine.. Plaquenil hydroxychloroquine and Azulfidine EN-tabs sulfasalazine delayed release tablets are used to treat rheumatoid arthritis. Plaquenil is also used to treat or prevent malaria, and to treat symptoms of discoid or systemic lupus erythematosus. If the plaquenil is helping and they say you need it, I'd take it - the side effects will go away. I've not had experience with sulfasalazine - but from what I've read, the side effects of that med are about the same as those of plaquenil. BTW - sulfasalazine is an anti-inflammatory. I have been diagnosed with Limited Scleroderma. My choices are Methotrexate, Plaquenil or Sulfasalzine Azulfidine. I researched them and determined Plaquenil would be my last choice, although it was his first, because I already have lattice degeneration of the retina in both eyes and one of the potential side effects is retinal problems.