Antidote of chloroquine

Discussion in 'Northwest Pharmacy' started by Farsh, 16-Mar-2020.

  1. Sempson New Member

    Antidote of chloroquine


    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

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    Chloroquine is a 4-aminoquinoline with antimalarial, anti-inflammatory, and potential chemosensitization and radiosensitization activities. Although the mechanism is not well understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite. In small children, the ingestion of 1-2 tablets of chloroquine is a potentially life-threatening ingestion. Chloroquine is on the list of ‘two pills that can kill‘ toddlers. The worst case scenario is an ingestion of 310mg/15kg = ~21 mg/kg. In general 10mg/kg is considered toxic, with increasing mortality at doses 30mg/kg. Chloroquine is an antimalarial medication which is used in the treatment as well as prophylaxis of malaria. This medicine is not recommended in patients with the eye disease. Liver function and blood cell count monitoring is necessary while receiving this medicine. Know Chloroquine uses, side effects, dosage, contraindications, benefit, interactions, purpose, drug interactions, precautions.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Antidote of chloroquine

    Chloroquine confirmed as anti-viral drug for Coronavirus, Chloroquine poisoning • LITFL • Clinical Case Tox Conundrum

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  6. Find patient medical information for Chloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.

    • Chloroquine Oral Uses, Side Effects, Interactions, Pictures..
    • Chloroquine - Uses, Dosage, Side Effects, Composition & more..
    • Chloroquine MedlinePlus Drug Information.

    Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat. Chloroquine is a drug used for preventing and treating malaria. The disease is transmitted by the bite of a mosquito. The Chloroquine drug is also used for treating liver disease caused by protozoa. It is rapidly acting erythrocytic schizonticide; controls most clinical attacks in 1-2 days with disappearance of parasites from peripheral blood. Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication.

     
  7. VD Guest

    After seeing my rheumatologist, he wants to put me on Plaquenil, mostly because I complained of recent onset of thinning/loss of hair which is freaking me out. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus Lupus Hair Loss Pictures, Symptoms, Treatment, Prevention, and More Hydroxychloroquine Plaquenil and Hair Loss Is my Plaquenil.
     
  8. komred User

    Plaquenil is the brand name for the prescription drug hydroxychloroquine. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses The Risk of Retinal Toxicity with Plaquenil
     
  9. IlyaT Well-Known Member

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