Chloroquine vs quinine

Discussion in 'Plaquenil' started by mal001, 16-Mar-2020.

  1. Chloroquine vs quinine


    Quinine is a basic amine and is usually provided as a salt. Various existing preparations include the hydrochloride, dihydrochloride, sulfate, bisulfate and gluconate.

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    For pregnant women diagnosed with uncomplicated malaria caused by chloroquine-resistant P. falciparum infection, women in the second and third trimesters can be treated with artemether-lumfantrine, and for all trimesters, mefloquine or a combination of quinine sulfate and clindamycin is recommended. Quinine treatment should continue for 7 days for infections acquired in Southeast Asia and for 3 days for infections acquired elsewhere; clindamycin treatment should continue for 7 days. Warning for non-medical redditors Chloroquine is promising, but it's possible to OD on it and cause blindness among other things, especially if you have certain genetics. DIY not encouraged! Is anyone researching that, or are any of the regions fighting the outbreak trying that proactively? It continued to be used for its antimalarial properties until the 1920s, when other drugs with fewer side effects took its place, like chloroquine. That's almost 300 years of use. And somewhere along the way, quinine found its way into our cocktails.

    All quinine salts may be given orally or intravenously (IV); quinine gluconate may also be given intramuscularly (IM) or rectally (PR). In the United States, quinine sulfate is commercially available in 324-mg tablets under the brand name Qualaquin.

    Chloroquine vs quinine

    Chloroquine Oral Uses, Side Effects, Interactions, Pictures., Post-exposure Chloroquine Prophylaxis COVID19

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  7. Chloroquine needs to be taken 1-2 weeks before traveling to an area with malaria, compared to some alternatives that can be taken 1-2 days before. chloroquine is only effective against malaria from certain areas of the world. chloroquine may worsen psoriasis, seizures, hearing problems, and liver conditions.

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    Quinine was the only effective treatment for malaria for 300 years. After World War II, however, it was largely supplanted by synthetic drugs such as chloroquine that were safer, more effective, and easier to make. Though quinine kills malarial parasites in red blood cells and alleviates fever. The role of rectal quinine as pre-referral treatment for severe malaria has not been fully explored, but it remains a promising intervention. In pregnancy, quinine continues to play a critical role in the management of malaria, especially in the first trimester, and it will remain a mainstay of treatment until safer alternatives become available. Quinine remains an important and effective treatment for malaria today, despite sporadic observations of quinine resistance. 1 Chloroquine. Research by German scientists to discover a substitute for quinine led to the synthesis in 1934 of Resochin chloroquine and Sontochin 3-methyl-chloroquine.

     
  8. aaa.seo User

    Applies to hydroxychloroquine: oral tablet Along with its needed effects, hydroxychloroquine (the active ingredient contained in Plaquenil) may cause some unwanted effects. How to Succeed in Plaquenil Screenings Influence of hydroxychloroquine on the bioavailability of. Review article prescribing medications in patients with.
     
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  10. Hydroxychloroquine Oral Route Description and Brand. Hydroxychloroquine is used to treat discoid lupus erythematosus DLE or systemic lupus erythematosus SLE or lupus. It is also used to treat acute and chronic rheumatoid arthritis. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms Tablet; Before Using

    Hydroxychloroquine - Wikipedia
     
  11. Dylan New Member

    Label CHLOROQUINE PHOSPHATE- chloroquine phosphate tablet. Mar 17, 2014 Each 250 mg tablet of chloroquine phosphate is equivalent to 150 mg base. In infants and children the dosage is preferably calculated on the body weight. Malaria Suppression— Adult Dose 500 mg = 300 mg base on exactly the same day of each week. Pediatric Dose The weekly suppressive dosage is 5 mg calculated as base, per kg of body weight, but should not exceed the adult dose regardless of weight.

    Chloroquine - FDA prescribing information, side effects and uses