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Ciprofloxacin vs doxycycline

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    Ciprofloxacin vs doxycycline


    We compared 7-day regimens of ciprofloxacin in dosages of 7 mg twice daily with doxycycline 100 mg twice daily for the treatment of nongonococcal urethritis in 178 men enrolled in a prospective, randomized, double-blind trial. The overall clinical response was comparable in the three treatment groups at both 2 and 4 weeks after therapy. However, among patients who initially had cultures positive for chlamydia, Chlamydia trachomatis was reisolated within 4 weeks after treatment in none of 10 doxycycline-treated patients, in 11 (52%) of 21 patients treated with 750 mg of ciprofloxacin twice daily, and in six (38%) of 16 patients treated with 1000 mg of ciprofloxacin twice daily. Each of the recurrent strains was identical in serotype to the original infecting strain. We conclude that ciprofloxacin in dosages as high as 2 g daily is inadequate for treatment of chlamydial urethritis in men, often resulting in relapsing infections.(JAMA. effects of antabuse BACKGROUND Rhinoscleroma is a chronic inflammatory condition in which deforming masses of tissue distend the nasal cavity. Klebsiella rhinoscleromatis is the causative agent. Antibiotic therapy traditionally consisted of streptomycin and tetracycline. But longterm therapy results in adverse side effects and poor patient compliance, hence this study to search alternative agents. MATERIALS AND METHODS This is a prospective study of 60 cases of rhinoscleroma visiting to the Department of ENT, KIMS, for a period of two years. RESULTS After 8 weeks treatment in the atrophic and granulomatous group, 6 (60%) became histopathologically negative and 4 (40%) remained histopathologically positive. The treatment was continued for another 4 weeks in positive cases and at the end of 12 weeks, 8 (80%) turned histopathologically negative, 2 (20%) remained positive. CONCLUSION We conclude that ciprofloxacin is a very good alternative drug compared to doxycycline in the treatment of rhinoscleroma particularly in the early stages of the disease and complete cure can be achieved by early diagnosis and treatment.

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    Whereas melioidosis is a significant cause of morbidity in south-east Asia, glanders is extremely rare. The efficacies of ciprofloxacin and doxycycline were assessed against a strain of Porton outbred mice and Syrian hamsters were given 40 mg/kg of either doxycycline or ciprofloxacin twice daily by sc injection according to one of three regimens: dosing starting 48 h before challenge and continuing for 5 days postchallenge; 5 days' therapy starting immediately after challenge; 5 days' therapy starting 24 h after challenge. Mice were challenged ip with , neither antimicrobial was effective when used therapeutically. The timely administration of either antimicrobial, however, was effective in preventing symptomatic infection. Doxycycline was the superior of the two antimicrobials against experimental glanders although relapse did occur in treated animals approximately 4–5 weeks after challenge. Whereas melioidosis is an important cause of mortality and morbidity in south-east Asia, northern Australia and the Indian sub-continent, glanders is extremely rare and is generally confined to equine disease in some parts of the Middle East, Asia and South America. A second consideration is that, perhaps fluoroquinolones may be useful for immediate therapy or as prophylaxis for individuals known to have been exposed, or at high risk of exposure, to melioidosis, particularly as there is no current means of immunoprophylaxis. Vibramycin (doxycycline) is good for treating many bacterial infections, but can increase your skin's sensitivity to sunlight and make you more likely to get a sunburn or rash.

    Ciprofloxacin vs doxycycline

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    Scand J Infect Dis Suppl. 1989;-5. Ciprofloxacin versus doxycycline in the treatment of uncomplicated urogenital Chlamydia trachomatis infections. buy aciclovir tablets online Definitive guide for SIBO Treatment. This article shows efficacy of antibiotics and SIBO diets and gives you sound recommendations for treating SIBO. Eur J Clin Microbiol Infect Dis. 1988 Oct;75658-61. Clinical efficacy of ciprofloxacin versus doxycycline in the treatment of non-gonococcal urethritis in males.

     
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