24 hours after lesion onset) Suppressive therapy (immunocompetent patients): 1 g/day PO Suppressive therapy (immunocompetent patients with ≤9 recurrences annually): 500 mg/day PO; transmission reduction for source partner, 500 mg/day PO Suppressive therapy (HIV-infected patients): 500 mg PO q12hr Thrombotic thrombocytopenic purpura (TTP)/hemolytic uremic syndrome (HUS) reported in patients with advanced HIV disease and in allogenic bone marrow transplant and renal transplant recipients Acute renal failure (ARF) may occur, especially in elderly patients or those with underlying renal impairment receiving higher than recommended doses; use with caution in patients with renal impairment, the elderly, and/or patients receiving nephrotoxic drugs Treatment should begin with the earliest symptom (tingling, burning, itching) in cold sores; for genital herpes, it should begin at the first signs and symptoms (within 72 hours of onset of first diagnosis or 24 hours of onset of recurrent episodes); for herpes zoster, it should begin within 72 hours of onset of rash; for chicken pox, it should begin with the earliest sign or symptom Central nervous system (CNS) effects may occur (eg, agitation, hallucinations, confusion, encephalopathy); risk of CNS adverse effects is higher in elderly patients Adequately hydrate patient; decreased precipitation in renal tubules may occur Metabolized by liver; valacyclovir is rapidly and nearly completely converted to acyclovir and L-valine via first-pass effect; acyclovir is hepatically metabolized to a very small extent by aldehyde oxidase and by alcohol and aldehyde dehydrogenase (inactive metabolites) The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information. clonidine for autism These highlights do not include all the information needed to use VALTREX safely and effectively. VALTREX (valacyclovir hydrochloride) Caplets Initial U. The efficacy of VALTREX initiated after the development of clinical signs of a cold sore (e.g., papule, vesicle, or ulcer) has not been established. Approval: 1995 (valacyclovir hydrochloride) Caplets are indicated for treatment of cold sores (herpes labialis). VALTREX is indicated for treatment of the initial episode of genital herpes in immunocompetent adults. The efficacy of treatment with VALTREX when initiated more than 72 hours after the onset of signs and symptoms has not been established. VALTREX is indicated for treatment of recurrent episodes of genital herpes in immunocompetent adults. The efficacy of treatment with VALTREX when initiated more than 24 hours after the onset of signs and symptoms has not been established. VALTREX is indicated for chronic suppressive therapy of recurrent episodes of genital herpes in immunocompetent and in HIV-1─infected adults. Azithromycin 5 day pack Metformin vs glyburide The Related Drug Information Index provides comprehensive access to all drug information related to a specific drug Types of content include full prescribing information, drug summaries, Full Prescribing Information Continuing Medication Education Full PI CME, Medication Guides, Risk Evaluation and Mitigation Strategies REMS Summaries, REMS. sertraline interactions Valaciclovir is known as a pro-drug. Once inside your body it is broken down into an active ingredient called aciclovir. Read Valaciclovir for viral infections - Valtrex These highlights do not include all the information needed to use VALTREX safely and effectively. See full prescribing information for VALTREX. VALTREX valacyclovir hydrochloride Caplets Initial U. S. Approval 1995 Depakene patient information (in plain English) VALTREX (valacyclovir hydrochloride) is the hydrochloride salt of L-valyl ester of the antiviral drug acyclovir (ZOVIRAX® Brand, Glaxo Smith Kline). Each caplet contains valacyclovir hydrochloride equivalent to 500 mg or 1 gram valacyclovir and the inactive ingredients carnauba wax, colloidal silicon dioxide, crospovidone, FD&C Blue No. 2 Lake, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, povidone, and titanium dioxide. The blue, film-coated caplets are printed with edible white ink. The chemical name of valacyclovir hydrochloride is L-valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester, monohydrochloride. It has the following structural formula: Valacyclovir hydrochloride is a white to off-white powder with the molecular formula C-HCl and a molecular weight of 360.80. The maximum solubility in water at 25°C is 174 mg/m L. The pka's for valacyclovir hydrochloride are 1.90, 7.47, and 9.43. The dose in immunocompromised patients is 1000 mg three times daily for at least seven days (3000 mg total daily dose) and for 2 days following crusting of lesions. This dose should be reduced according to creatinine clearance (see Renal impairment below). For recurrent episodes, treatment should be for three to five days. For initial episodes, which can be more severe, treatment may have to be extended to ten days. For recurrent episodes of herpes simplex, this should ideally be during the prodromal period or immediately upon appearance of the first signs or symptoms. Valtrex can prevent lesion development when taken at the first signs and symptoms of an HSV recurrence. For herpes labialis (cold sores), valaciclovir 2000 mg twice daily for one day is effective treatment in adults and adolescents. The second dose should be taken about 12 h (no sooner than 6 h) after the first dose. Valtrex prescribing information Therapeutic Class Overview Antivirals, Herpes, Valaciclovir for viral infections - Valtrex. Side effects; dosage Amoxicillin for epididymitis Viagra coupon code VALTREX® Tablets NAME OF THE MEDICINE Valaciclovir DESCRIPTION Valaciclovir is the L-valine ester of aciclovir. Its chemical name is 2-2-amino-1,6-dihydro-6-oxo-9H-purin-9-ylmethoxyethyl l-valinate hydrochloride. VALTREX Tablets NAME OF THE MEDICINE Valaciclovir These highlights do not include all the information needed to. Valacyclovir prescribing information - MedHelp Concise Prescribing Info Full Prescribing info Indications / Uses Dosage / Overdosage. Click to view detailed Valtrex Dosage/Direction for Use. valacyclovir 500mg tablets VALTREX safely and effectively. See full prescribing information for. VALTREX. VALTREX. ®. valacyclovir hydrochloride Caplets. Initial U. S. Approval 1995. Medscape - Herpes simplex, zoster-specific dosing for Valtrex valacyclovir, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.